STABILITY STUDIES ON DICLOFENAC SODIUM CREAM
نویسندگان
چکیده
منابع مشابه
Stability studies on aqueous and oily ophthalmic solutions of diclofenac.
Various aqueous and oily diclofenac ophthalmic formulations were subjected to accelerated and long term stability studies. Degradation of diclofenac was found to follow first-order kinetics. Among the aqueous formulations containing preservative, formulation with PMA, PMN, SA, MP/PP and SMS showed diclofenac content above 90% after 6 months of accelerated and 12 months of room temperature stora...
متن کاملIMPROVED CHROMATOGRAPHIC METHOD FOR DETERMINATION OF SODIUM DICLOFENAC IN INJECTABLE SOLUTION AND PREDICTION OF CHEMICAL STABILITY
Two modified methods for assaying sodium diclofenac were developed by GC and HPLC. Diclofenac was converted into methyl ester derivative by methyl iodide in acetone. The ester was extract and subjected to GLC with flame ionization detector. %5 SE-30/chrom W-HP (80-100 mesh) was used as a column in GC. For reversed phase HPLC, the mobile phase was methanol and water (55-45). The separation was p...
متن کاملAntibacterial Effect of Diclofenac Sodium on Enterococcus faecalis
OBJECTIVE Non-steroidal anti-inflammatory drugs (NSAIDs) have shown antibacterial activity in some recent studies. The aim of this study was to evaluate the antibacterial effect of diclofenac against Enterococcus faecalis (E. faecalis) as a resistant endodontic bacterium in comparison with ibuprofen, calcium hydroxide and amoxicillin. MATERIALS AND METHODS The antibacterial activity of materi...
متن کاملA comparative evaluation of diclofenac sodium transdermal patch, oral diclofenac sodium with intramuscular injections of diclofenac sodium in patients suffering from oral pain: A randomized control trial
Background Newer drug delivery systems such as transdermal patches using pain relieving or modifying agents emerged as a mainstream treatment protocol for management of pain on the outpatient basis. The administration of diclofenac 100 mg in the transdermal patch in the patients having dental pain due to periapical/periodontal infections was evaluated. Materials and Methods Ninety patients of...
متن کاملIn vitro investigation of sodium diclofenac adsorption on sucralfate.
Adsorption of sodium diclofenac was investigated in the presence of sucralfate--a cytoprotective agent preventing gastropathy, adverse effect of diclofenac. Evaluation of adsorption was performed by means of a static method in vitro taking into account pH of the environment, temperature, concentration of the investigated agents and the form of sucralfate. Findings obtained prove that sodium dic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Advances in Pharmaceutical Analysis
سال: 2011
ISSN: 2277-9353
DOI: 10.7439/ijapa.v1i1.3